AstraZeneca vaccine faces resistance in Europe after health workers suffer side-effects

New Delhi: Health officials in some European countries are facing resistance to AstraZeneca’s COVID-19 vaccine, after which hospitalized staff and other front-line activists began to call the sick, already stretched Due to additional pressure on services.

Such symptoms, as reported in clinical trials for the AstraZeneca shot, may include a high temperature or headache and are a general indication that the body is causing an immune response. They usually wither once a day.

Other shots approved in Europe, developed by Pfizer and Modern, have been associated with similar temporary side effects, including fever and fatigue.

But AstraZeneca rolled out the latest, with health authorities in France issuing guidance to the stagger who gave the shot, two areas in Sweden halting vaccination and some required staff in Germany are refusing it.

A spokesperson for AstraZeneca said: “Currently, the responses are stated as we would expect based on the evidence collected from our clinical trial program.”

Those receiving the vaccine are closely watched through routine pharmacovigilance activities, the Anglo-Swedish drugmaker said, adding that it was continuing to keep a close watch on the situation.

“No serious serious incidents have been confirmed,” the spokesman said.

In France, which began shooting AstraZeneca on 6 February, staff at a hospital in Normandy experienced stronger side-effects than alternative vaccines from Pfizer and German partner BioNotech.

“AstraZeneca caused more side effects than the Pfizer vaccine,” said Melanie Cottge, communications manager at Saint-Lo Hospital in Normandy.

“Between 10% and 15% of vaccinators can have side effects from this vaccination, but it only goes away with fever conditions, fever, nausea and within 12 hours.”

Following similar reports from other hospitals, the French Medicines Safety Agency said on 11 February that such side effects were “known and described”, but should be subject to surveillance regarding their intensity.

It issued guidance for the vaccination of front-line staff working together in teams to reduce the risk of discontinuation in the operation.

The agency advised after receiving 149 alerts of frequent flu-like side effects from the AstraZeneca vaccine. A total of 10,000 people received shots nationwide during this period.

Some US hospitals and other organizations with front-line staff adopted a similar strategy when the country began the vaccination program in December. The United States is managing shots from Pfizer / BioNotech and Modern.

In the UK, the home of the AstraZeneca vaccine, developed at the University of Oxford, is designed to make vaccination readily available to hospital staff. The more jobs shift, the more naturally they are out of the process.

France’s issues highlight how some doctors and hospitals are still learning how governments run to prevent the epidemic and race to acquire weapons as soon as possible.

This is the latest setback for a French vaccination campaign that has been criticized for its slow start. Last week, the government said that just over 3% of the population received their first dose.

In Sweden, two out of 21 healthcare sectors stopped vaccination of workers last week, when AstraZeneca became ill after being shot.

The Sorland and Gavleborg regions said that out of 400 people vaccinated, about 100 people had fever or fever-like symptoms. Most cases were mild and consistent with the previously reported side-effects.

Both regions said they would resume vaccination, and the Swedish Medical Products Agency saw no reason to change their vaccination guidelines.

AstraZeneca’s vector-based vaccine is the third to win regulatory approval in the European Union.

As part of a positive recommendation from the European Medicine Agency on 29 January, Sentinel concluded that it was about 60% effective, while over 90% for Pfizer / BioNTech and Moderna vaccines.

It also considers the product safe to use and it will regularly monitor reports of side-effects.

In Germany, Health Minister Jens Spann on Wednesday responded to reports that essential workers were reluctant to receive an AstraZeneca shot after some experienced strong side effects, saying it was both safe and effective.

According to data from the Ministry of Health and the Robert Koch Institute, Germany has taken 737,000 dose deliveries from AstraZeneca, but only 107,000 have been administered.

“This vaccine is a great way to prevent severe COVID disease,” said the Ministry of Health in the eastern state of Saxony. “Nevertheless, we note that there are still vaccinated vaccination dates for AstraZeneca.

Agency Input